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Oncology Research

Leighton Hospital’s Oncology Research Department is actively involved in clinical research and have many studies currently open to recruitment across 9 different disease areas.

If you would like to know more about getting involved in any clinical research in any of these areas please contact the Oncology Research Department on 01270 273486

OPEN TRIALS

 

Name of Study

Topic Area

Trial to Assess;

Principal Investigator

Closes

Bridging the Age Gap in Breast Cancer:

 

Breast

Improving outcomes for older women

Miss Pope

 

30/06/2017

FH02

Breast

Mammographic Surveillance in women aged 35 - 39 at enhanced familial risk of breast cancer

Dr Troop

 

31/12/2013

 

B – AHEAD 2

Breast

Breast Activity and Healthy Eating After Diagnosis  - 2 : during Chemotherapy for early breast cancer

Dr Armstrong

26/03/2014

 

Head and Neck 5000 -

Head and Neck

 

The aim of the research is to look at care for people with head and neck cancer

 

 

Margaret Doyle

 

31/12/2014

 

Melanoma Lifestyle

Dermatology

 

 

Investigate the role, in particular of diet and drugs, in determining whether melanoma comes back after diagnosis or not.

 

Dr Burt

September 2014

 

MDS Bio

Haematology

 

Bone marrow function in normal subjects and in patients being investigated for a possible blood cell abnormality. A research study looking at how blood cells are made and what happens when this goes wrong

Dr Stewart

February 2017

 

PACIFICO

Haematology

 

Purine-Alkylator Combination In Follicular lymphoma Immuno-Chemotherapy for Older patients: a phase III comparison of first-line R-CVP versus R-FC lite. The aim of the PACIFICO trial is to compare “R-FC lite” to the drug combination currently regarded as the standard of care (“R-CVP”) to see which is better.

 

Dr Karunanithi

January 2019

TEAMM

Haematology

 

Tackling Early Morbidity and Mortality in Myeloma: Assessing the benefit of antibiotic prophylaxis and its effect on healthcare associated infections

Dr Karunanithi

 

30/11/2015

 

PIT

Lung

A phase III Randomised trial of Prophylactic Irradiation of Tracts in patients with Malignant Pleural Mesothelioma Following Invasive Chest Wall Intervention

Dr Burt

 

30/06/2015

Janssen Prostate Cancer Registry

Urology

 

A Prospective Registry of Patients With a Confirmed Diagnosis of Adenocarcinoma of the Prostate Presenting With Metastatic Castrate-Resistant Prostate Cancer

 

Dr Wylie

 

 

January 2019

RADICALS

Urology

 

Radiotherapy and Androgen Deprivation In Combination After Local Surgery– A randomised controlled trial in prostate cancer

 

Dr Wylie

 

June 2014

 

STAMPEDE

Urology

 

Systematic Therapy in Advancing or Metastatic Prostate Cancer : Evaluation of Drug Efficacy

 

Dr Wylie

 

31/12/2020

 

UKGPCS

Urology

 

UK Genetics Prostate Cancer Study: Epidemiology and Molecular Genetic Studies

 

Dr Wylie

 

31/12/2017

 

NSCCG

Colorectal

 

National Study of Colorectal Cancer Genetics

Dr Braun

 

2015

 

Surgical Wellbeing

Surgical

 

A questionnaire study on the association of surgery with patients’ wellbeing

 

Mr Khan

 

 

POSICC

Surgical

A Single Blind Randomised Controlled Trial for Pre-operative Oral Supplementation in Colorectal Cancer Patients

 

Mr Khan

 

 

 

TVT

Palliative Care

Comparing  a two step approach for cancer pain relief with the standard 3 step approach of the WHO analgesic ladder

Dr Smith

16/01/2016

Compare

Prostate

Comparing treatment options for Prostate Cancer – evaluating patient preferences for the treatment of localised prostate cancer

Dr Wylie

27/08/2014

ESPAC4

Upper GI

 

Combination versus single agent chemotherapy in resectable pancreatic ductal and peri-ampullary cancers

Dr Jamil

 

01/11/2014

 

GO - 2

Upper GI

Alternative chemotherapy for frail or elderly patients with advanced gastric or oesophageal cancer

Dr Jamil

31/08/2016

 

 

 

 

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